Research test kit ACCEL-AMPLICON® PLUS LYNCH
for cancers

research test kit
research test kit
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Applications
for research, for cancers

Description

The Accel-Amplicon Plus Lynch Syndrome Panel is the NGS multigene panel to identify mutations in DNA Mismatch Repair (MMR) genes. It offers comprehensive and exon-level hotspot coverage of 4 clinically-relevant genes: MLH1, MSH2, MSH6 and PMS2. And with sensitivity down to 1% allele frequency, now you can identify both germline and somatic mutations in the same panel. Comprehensive: Covers 600 COSMIC and 7,500 ClinVar mutations and generates targeted libraries compatible with Illumina® sequencing platforms. Powerful: Simultaneous detection of single nucleotide variants (SNV) and small insertion and deletions (indels), all within a fast and easy single-tube assay workflow. Other key features include: Robust performance on cell-free DNA and FFPE samples starting with as little as 10 ng input. Highly sensitive detection of rare variants down to 1% allele frequency. Easy, single-tube assay with sequence ready libraries in 2 hours. Streamlined analysis with new bioinformatics tools including Primerclip or VarSome. Compatible with all Illumina sequencers The Lynch Syndrome Panel offers comprehensive coverage of 4 clinically-relevant Lynch Syndrome genes. The panel covers over 600 COSMIC and 7,500 ClinVar mutations and generates targeted libraries compatible with Illumina® sequencing platforms. This panel enables: • Compatibility with wide range of samples • Data analysis options including Primerclip and Genialis • Addition of your own custom content Product Specifications Amplicons 180 Average Amplicon Size 140 bp Number of Genes 4 Gene List MLH1, MSH2, MSH6, PMS2 Total Target 15 kb Input Recommended 10 ng amplifiable DNA

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