Microbial enumeration system MD500 offline

Introduction
The MD500 Offline Microbial Detection Analyzer combines laser-induced fluorescence and Mie scattering particle measurement to count individual microorganisms in relatively pure water streams. Designed for continuous bioburden monitoring, it delivers real-time alerts without waiting for culture plate results and requires no reagents or sample preparation.

Key features

• Measurement range 0–10,000 AFU/mL with a detection limit of 1 AFU and minimum particle detection size of 0.1 μm.
• Reagent-free operation with full touchscreen interface for straightforward on-site use.
• Multiple output formats: configurable 4–20 mA, analog/digital channels, Ethernet/Modbus TCP, USB and Wi‑Fi for SCADA integration.
• Built-in methods and automated maintenance: one-key flushing, continuous monitoring of up to 10 channels (expandable to 100).
• Designed for pharmaceutical and process environments: supports GMP and 21 CFR Part 11 requirements with four levels of password permissions, audit trail and multiple backup options.

Applications

• Inline monitoring of injection water and purified water.
• Rinse water and product solution control.
• Ultra-pure water and natural drinking water surveillance where low-burden detection is required.

Technical specifications

• Measurement range: 0–10,000 AFU/mL
• Minimum detection size: 0.1 μm
• Detection limit: 1 AFU
• Response time: real-time
• Analysis mode: continuous operation
• Sample temperature: 5–90 ℃
• Flow rate: 1.5–30 mL/min
• Ambient conditions: 0–50 ℃, up to 80% RH
• Channels: 1–10 supplied, expandable to 100
• Power supply: 100–240 VAC, 50/60 Hz
• Inlet connection: 1/8 inch (3.2 mm) OD
• Weight: 10 kg
• Data outputs: configurable 4–20 mA, analog/digital outputs, Ethernet/Wi‑Fi, Modbus TCP, USB

Compliance & data management

• Audit-ready design to support GMP and 21 CFR Part 11 compliance.
• Four user permission levels and full audit trail for secure data integrity.
• Multiple backup and export options; SCADA connectivity via Modbus TCP for centralized monitoring.

Options & installation

• Expandable channel architecture to scale from single-channel monitoring to up to 100 channels.
• Multiple signal interfaces for easy integration with plant control systems.
• Compact footprint and reagent-free design simplify installation and reduce routine consumables.