OverviewINÜO is a professional dermofacial system by Termosalud that combines targeted functional cosmetics (Üceuticals) with integrated technologies to prevent, protect and repair structural skin aging through a multilayer treatment protocol acting from deep dermis to epidermal surface.
Core conceptINÜO addresses daily internal and external aggressors that compromise barrier integrity, microbiome balance and regenerative capacity by deploying a stepwise strategy to:
- Protect the skin barrier, microbiome and immune balance
- Block molecular aggressors such as glycation and oxidative degradation
- Reactivate regenerative signaling and fibroblast function to restore dermal structure and hydration
Key benefits- Reinforces epidermal barrier and supports microbiome eubiosis
- Limits glycation and oxidative damage in dermal structures
- Reactivates regenerative pathways (collagen, elastin, GAGs) and fibroblast activity
- Delivers layered outcomes from immediate decongestion to long-term structural repair
Dermofacial technologies included- MASSAGE — facial lymphatic and circulatory activation: drains, activates and decongests to enhance clearance and product integration
- O2XY — oxygenation module: controlled exfoliation and local oxygen activation (ÜPOD + Activating Gel) to increase tissue oxygenation and readiness for absorption
- NFUSE — precision infusion and suction with disposable diamond tips: gentle exfoliation and targeted serum delivery with flow and vacuum control
- ULTRAPULSE + HYALMAX — athermal high-frequency ultrasound plus hyaluronic stimulation: transiently increases permeability and stimulates dermal renewal and ECM synthesis
- CHROMIX — LED photobiomodulation with selectable wavelengths (Infrared, Blue, Red) to modulate inflammation, balance microbiota and stimulate repair
Protocol steps (multilayer treatment strategy)- Step 1 — MASSAGE: drains · activates · decongests
- Step 2 — O2XY: cleans · exfoliates · oxygenates — prepares tissue for absorption
- Step 3 — NFUSE: infuses · nourishes · hydrates — precision serum delivery to targeted layers
- Step 4 — ULTRAPULSE & HYALMAX: integrates · stimulates · builds — ultrasound-enhanced permeability and ECM stimulation
- Step 5 — CHROMIX: regenerates · protects · soothes — photobiomodulation to extend and consolidate effects
CHROMIX wavelengths and actions- Infrared (IR): anti-inflammatory and immunomodulatory effects
- Blue light: balances skin microbiota and controls acne-related bacteria
- Red light: stimulates collagen synthesis and optimizes cellular metabolism
Integrated functional cosmetics (Üceuticals)Üceuticals is the dedicated line formulated to protect from core biological mechanisms outward, counteracting glycation and oxidation while supporting barrier and microbiome. Key product families used within the protocol:
- Üceuticals core formulas
- ZERO PEEL — progressive epidermal renewal for sensitive or barrier-compromised skin
- OXYGENATING PEEL — ÜPOD + Activating Gel to boost local oxygenation and prepare skin
- TRIOME+™ — antioxidant and anti-glycation complex
- Facial serums (Light Up, Clear Reset, AGE Strategy, Ceramide Reload, etc.)
- Revitalizing Biomask — soothing and barrier-reinforcing mask
Molecular & physiological effects- Blocks glycation progression and reduces oxidative degradation in dermal matrix
- Strengthens epidermal barrier via biomimetic lipids and ceramides to limit TEWL
- Modulates subclinical inflammation and restores microbiome balance
- Stimulates fibroblasts and supports collagen, elastin and GAG synthesis
- Enhances lymphatic drainage to reduce oedema and clear metabolic waste
Clinical approach and resultsINÜO is adaptable to anti-aging, barrier repair, oily/imperfection-prone skin and preventive protocols. Clinical case series include single-session revitalizing treatments and multi-session (eg. 3-session) anti-aging protocols combining peels, targeted serums, ultrasound stimulation (HYALMAX/ULTRAPULSE) and LED (CHROMIX) with documented improvements in texture, hydration and dermal density.
Technical specifications- Product: INÜO dermofacial system
- Manufacturer / Brand: Termosalud
- System components: MASSAGE, O2XY oxygenation module, NFUSE infusion/suction unit with disposable diamond tips, ULTRAPULSE (athermal ultrasound) + HYALMAX stimulation, CHROMIX LED module
- Protocol: 5-step multilayer protocol combining technologies and Üceuticals cosmetic line
- Intended use: professional dermofacial treatments for prevention, barrier repair, microbiome balance, anti-aging and revitalization
- Key cosmetic complexes: TRIOME+™, ÜPOD + Activating Gel, Revitalizing Biomask, targeted serums
- Therapeutic targets: glycation, oxidation, barrier deterioration, fibroblast senescence, impaired hydration, microbiome imbalance