Industrial Mass Spectrometry
While analysis of denatured proteins may be the most common LC/MS protein analysis, many biopharmaceutical and biological research applications require analysis of proteins in their native (intact) state. The Thermo Scientific™ Exactive™ Plus EMR mass spectrometer combines unsurpassed high-resolution accurate-mass Thermo Scientific™ Orbitrap™ analysis with an extended mass range (EMR) option to create an outstanding tool for investigating the structure, topology, and architecture of native-like tertiary and quaternary protein structures.
Confidently Identify, Characterize, and Quantify Intact Proteins
Extended m/z 350–20,000 mass range enables analysis of larger proteins, antibodies, antibody-drug conjugates, glycoforms, and protein assemblies
Improved transmission of higher-mass ions provides stronger signals
Resolving power up to 140,000 FWHM enables separation of isoforms and determination of glycosylation states
Excellent mass accuracy ensures confident identification
Access to short transients improves signal-to-noise ratios
Compatibility with Thermo Scientific Protein Deconvolution software designed specifically for identification and characterization of intact proteins
Modified HCD cell controls make it easier to optimize experimental conditions
Intuitive operating software reduces learning curves
For Research Use Only. Not for use in diagnostic procedures.