Amphotericin B reagent MycoRid™

antifungalsolutionfor research

MycoRid™ is a highly stable, solubilized aqueous formulation (1000x) of a polyene antifungal compound. It is a substitute for Amphotericin B (Fungizone). It has a lower level of cytotoxicity in cell culture due to the use of polysaccharide as a solubilizing agent, rather than sodium deoxycholate in Fungizone that has shown evidence of cytotoxicity in cell culture. MycoRid can be stored up to 3 months at 4°C, unlike Amphotericin B solution that is stable for one month at 4°C. Mechanism of Action: The active component of MycoRid™ has a similar mode of action to Amphotericin B (Fungizone). Polyene antimicrobials associate with membrane sterols in mammalian and fungal cell membranes and forms pores leading to essential ion leakage and ultimately, cell death. Applications Spectrum: MycoRid™ is active against fungal (molds and yeasts) cells and is not toxic to bacteria due to their lack of sterols. MycoRid™ is compatible with Pen-Strep solutions. Microbiology Applications: MycoRid™ is used as an antimycotic selective agent in several routinely used selective media formulations to inhibit the growth of background fungal growth.