Background
Elevated intraocular pressure is a known risk factor for the development and progression of glaucoma. Trabeculectomy was first described in the 1960s and is a form of guarded filtration surgery, designed to improve the outflow of aqueous from the eye. It is performed usually in cases where the medical management of intraocular pressure is suboptimal and clear structural/functional progression is occurring. This aqueous usually drains into the subconjunctival space, resulting in a characteristic bleb seen in such patients, and from there it is thought to drain into the aqueous veins or absorbed by surrounding vascular or perivascular conjunctival tissue.
Indications
Progressive disease in the following groups:
Primary open angle glaucoma
Pseudoexfoliation glaucoma
Traumatic glaucoma
Angle closure glaucoma
Pediatric glaucoma (surgery should be performed by specialist pediatric glaucoma specialists in this instance)
Key objectives
To lower, and then stabilize the intraocular pressure, thereby slowing glaucoma progression.