Endodontic dental material ENDASEPT

geltemporaryantiseptic

Antiseptic gel based on metronidazole and chlorhexidine Endasept The material is used for: treatment of the infected canals in case of gangrenous pulpitis and chronic forms of periodontitis; in acute periodontitis, and also after unsuccessful treatment with non-specific antiseptics or medication based on antibiotics and corticosteroids. Gel EndAsept contains antiseptics: metronidazole (10%), chlorhexidine bigluconate (2%), overwhelming anaerobic flora of root canals actively. Metronidazole possesses a wide spectrum of action concerning the elementary, obligate anaerobic bacteria (spore - and non-sporeformative), is active concerning bacteroides, phuso-bacteria, clostridia. The mechanism of antimicrobial action is to connect nitrogroup metronidazole with microbial DNA and terminate synthesis of nucleic acids in this regard. Chlorhexidine bigluconate is one of the most active local antiseptics, has a fast and strong bactericidal effect on gram-positive and gram-negative bacteria. The mechanism of action of chlorhexidine bigluconate is connected with its surface-active properties, an infringement of permeability cytoplasmic membrane of microbes occurs. Due to hydrophilic base gel is easily entered into canals, deeply impregnating dentinal tubules, and washed away from canals by water easily. Gel - 10 g