Product Name:Oncology Multi-Gene Mutation Detection Kit (Next Generation Sequencing)
Pack Size:16 Tests/Kit
32 Tests/Kit
Instruments Validated:Ion Torrent,Illumina
Tumor tissue:Peripheral blood,Pleural effusion
DETECTED GENES
NO. - GENE - - Covering Exons
1 - EGFR - - 18,19,20,21
2 - KRAS - - 2,3,4
3 - BRAF - - 15
4 - PIK3CA - - 10,14,21
5 - NRAS - - 2,3
6 - HER2 - - 19,20,21
7 - MET - - - 2,14,16,19
8 - AKT1 - - - 3
9 - KIT - - - 9,11,13,17
10 - PDGFRA - - 12,18
11 - ALK - - EML4-ALK(21kinds)
12 - RET - - - KIF5B、CCDC6、NCOA4、PCM1、GOLGA5、HOOK3、KTN1(15 kinds)
13 - ROS1 - - CD74、GOPC、SDC4、SLC34A2、EZR、LRIG3、TPM3-ROS1(15 kinds)
14 - MET - - 14 exon skipping mutation
DETECTION SIGNIFICANCE
Personalized Treatment:Select suitable target drugs for the patients based on the gene detection information to improve the efficacy of the drugs, thus realize personalized treatment.
Monitoring drug efficacy and Resistance: Analyze the drug resistance mechanism, adjust the treatment plan according to the gene variation information after drug resistance.