Product Name:Human Endometrial Cancer Molecular Classification Gene Mutation Detection Kit Pack Size:16 Tests/Kit
32 Tests/Kit
Instruments Validated:Ion Torrent, Illumina
Sample Type:Tumor tissue
Subtype - Treatment Guidance
POLE ultramutated - 1.Good prognosis (including high-grade G3);
2.Low risk of lymph node metastasis, no need to remove lymph nodes;
3.No adjuvnt therapy may be considered after surgery;
4.Immunotherapy benefit;
5.Conservative treatment may be considered for fertility requirements.
MSI-H - 1.The prognosis is moderate;
2.Postoperative radiotherapy does not require combined chemotherapy;
3.Immunotherapy benefit;
4.Lynch screening;
5.Less sensitive to hormone therapy.
CN-L - 1.The prognosis is moderate;
2.More sensitive to hormone therapy;
3.Whether postoperative radiotherapy needs to be combined with chemotherapy still needs clinical research.
CN-H - 1.Poor prognosis (including low-grade G1G2);
2.Require aggressive adjuvant therapy;
3.May not be suitable for fertility preservation.