SRS linear particle accelerator ZAP-X®

radiosurgerystereotactic radiosurgery

Overview
ZAP-X® Gyroscopic Radiosurgery® is a self-shielded, vault‑free radiosurgery platform designed specifically for streamlined treatment of brain tumors, intracranial lesions and other head & neck conditions. The system integrates no‑cobalt technology with a dedicated linear accelerator delivery and a spherical delivery workspace to enable highly conformal stereotactic radiosurgery while reducing infrastructure and recurring source costs.

Key benefits and clinical design highlights

• Vault‑free SRS delivery eliminates the need for heavy concrete/steel bunkers and associated infrastructure expense.
• No cobalt: dedicated linear accelerator avoids recurring radioactive source replacement and related regulatory overhead.
• Spherical workspace: dual independent gantries enable routine delivery of >1000 unique non‑coplanar beam angles for high conformality.
• Low collimation leakage: tungsten‑shielded circular collimation targets leakage <0.002% of the primary beam.
• Reduced penumbra and scatter: ~3 MV beam with SAD ≈45 cm yields substantially sharper penumbra and lower non‑therapeutic scatter to adjacent critical structures.

Clinical / regulatory notes
ZAP‑X® received U.S. FDA 510(k) clearance (2017), began clinical patient treatments in 2019, received Japan Shonin clearance (2020) and EU CE clearance (2021). Peer‑reviewed and open‑access publications document technical and clinical experience with the platform.

Design and technical advantages (summary)

• Vault‑free, self‑shielded gyroscopic radiosurgery platform enabling more flexible deployment options.
• Dedicated linear accelerator with platform‑stated capability (~1500 MU/min) for delivery efficiency.
• Approximately 3 MV beam energy optimized for SRS to reduce scatter compared with typical 6–10 MV multi‑purpose systems.
• Dual independent gantries providing a large spherical workspace and routine use of >1000 non‑coplanar beam angles.
• Tungsten circular collimation system for minimal leakage and precise dose sculpting.
• Large source‑axis distance (SAD ≈45 cm) to reduce beam penumbra and dose to organs‑at‑risk.

Featured installation sites (examples)

• Lingen, Germany — Bonifatius Hospital Lingen
• Clinton, Maryland, USA — MedStar Georgetown Cancer Institute at Southern Maryland Hospital Center
• Zurich, Switzerland — Swiss Neuro Radiosurgery Center (SNRC)
• Munich, Germany — European Radiosurgery Center (ERC)

Applications
Streamlined SRS treatments for primary and metastatic brain tumors, intracranial lesions and selected head & neck indications; intended to broaden access to stereotactic radiosurgery across urban, suburban, rural and outpatient settings.

Technical specifications

• Platform: ZAP‑X® Gyroscopic Radiosurgery® (vault‑free, self‑shielded)
• Beam source: dedicated linear accelerator (~3 MV equivalence)
• Accelerator output: platform‑stated performance (~1500 MU/min)
• Gantry configuration: dual independent gantries enabling a spherical workspace
• Beam angles: routine delivery of >1000 unique non‑coplanar beam angles
• Collimation: tungsten‑shielded circular collimation system; leakage <0.002% of primary beam
• SAD: ≈45 cm (enables ~50% penumbra reduction vs 100 cm SAD systems)
• Regulatory clearances: U.S. FDA 510(k) (2017), Japan Shonin (2020), EU CE (2021)
• Installation benefit: eliminates need for heavy shielding bunkers and recurring radioactive source replacement