CT scanner Pannoramic-X

Overview
The Pannoramic-X micro-CT scanner enables ultra-high-resolution 3D imaging of whole-FFPE tissue blocks, macroblocks and large specimens. The system supports virtual slicing, virtual staining and quantitative biomarker analysis using soft X-ray micro-CT and DVREAL 3D Imaging while preserving sample integrity for downstream digital pathology workflows.

Capabilities and workflow
Delivered with CT Control and an integrated software suite (3DView, PatternQuant, NuclearQuant), the Pannoramic-X provides volumetric reconstruction, AI-driven image processing and quantitative biomarker assessment. It integrates with digital pathology environments and supports DICOM, MRXS and RAW formats for storage, analysis and sharing.

Key features

• 3D digital pathology without physical sectioning, preserving intact tissue architecture for accurate analysis
• Ultra-high-resolution imaging of large specimens (whole‑FFPE blocks and macroblocks) with scans reported up to 300 mm
• DVREAL technology enabling virtual slicing and virtual staining for retrospective and multi-plane analysis
• Improved tumor morphology visualization enabling assessment of lymphovascular invasion, tumor budding and vascular structures
• AI-powered analysis via PatternQuant and NuclearQuant for automated pattern recognition and quantitative measurements
• High-throughput scanning with optional sample changer for multiple samples per run
• Seamless integration into digital pathology workflows with CT Control and 3DView; supports standard data formats
• Enclosed zero-emission design operable on standard laboratory power

Comparison with traditional histology

• 3D imaging: Pannoramic-X — full volumetric 3D analysis; Traditional histology — limited to 2D slices
• Sample integrity: Pannoramic-X — intact, no sectioning required; Traditional — tissue loss and sectioning artifacts
• Virtual slicing & staining: Pannoramic-X — unlimited retrospective analysis; Traditional — irreversible after sectioning
• Size limitations: Pannoramic-X — scans up to 300 mm (some modes reference ~150 mm); Traditional — limited to thin sections
• Tumor & biomarker analysis: Pannoramic-X — 3D visualization and AI-driven quantification; Traditional — manual 2D assessment

Applications and use cases
The Pannoramic-X is intended for cancer research, molecular pathology, digital histopathology, oncology research and pharmaceutical development. It is also suitable for non-destructive high-resolution volumetric imaging in fields such as paleontology, botany, geology and environmental science.

Technical specifications

• Commercial name: Pannoramic-X
• Imaging technology: Soft X-ray micro-CT with DVREAL 3D Imaging
• Software: CT Control, 3DView, PatternQuant, NuclearQuant (AI-powered analysis)
• Sample capacity: specimens reported up to 300 mm (30 cm); some modes reference up to 150 mm
• X-ray source: Micro-focus 70 kV, 7 W (upgrade to 250 W available)
• Scanning time: typically from ~20 minutes to several hours depending on resolution
• Operational mode: 24/7 continuous operation
• Multiple sample loading: optional sample changer for simultaneous samples
• Workstations: data acquisition CPU with 4K monitor; reconstruction CPU with 4K monitor
• Data output: DICOM, MRXS, RAW
• Dimensions (WxDxH): 1790 x 929 x 1820 mm (without monitor console)
• Weight: 1150 kg (recommended floor space 2000 x 2800 mm; floor load <500 kg/m²)
• Radiation safety: enclosed zero-emission system; no special facility modifications required
• Power: operates on standard laboratory electricity