Recombinant antigen reagent RP01260LQ

for researchSARS-COV-2

Recombinant SARS-COV-2 S1+S2 ECD (S-ECD) Protein with His tag (Wild type, pre-fusion state plus post-fusion state) is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val11-Gln1208) of SARS-COV-2(2019-nCoV) S1+S2 ECD (S-ECD) (Accession #YP_009724390.1) fused with a 6×His tag at the C-terminus. Bio-Activity - Measured by its binding ability in a functional ELISA. Immobilized Recombinant SARS-COV-2 Spike S1+S2 ECD-His at 2μg/mL (100 μL/well) can bind Recombinant Human ACE2 with a linear range of 0.15-9.92 ng/mL. Endotoxin - < 0.1 EU/μg of the protein by LAL method. Formulation - Supplied as a 0.22 μm filtered solution in PBS, pH 7.4.Contact us for customized product form or formulation.Contact us for customized product form or formulation. Calculated MW - 133.8kDa Background The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates thisinteraction.The S protein plays key parts in the induction of neutralizing-antibody and T-cellresponses, as well as protective immunity. Product information Synonym - cov spike Protein; 2019-nCoV; ncov spike Protein; 2019-nCoV; coronavirus spike Protein; 2019-nCoV; S glycoprotein; COVID-19; S protein; Spike glycoprotein Expressed Host - HEK293 cells