Fully automated immunochemistry analyzer DxC 500i

for clinical diagnosticwith ISEwith ion-selective electrode

Overview
The DxC 500i Clinical Analyzer provides integrated clinical chemistry and immunoassay testing in one random-access system, designed for low- to mid-volume laboratories to deliver consistent, commutable patient results with streamlined operation.

Key benefits

• High availability and serviceability to minimize downtime
• Commutable patient results across chemistry and immunoassay methods
• Broad assay portfolio including extensive chemistry and immunoassay menus
• Optimized workflow to reduce hands-on time and speed critical results

Standardized features

• Shared reagents and consumables compatible with legacy Beckman Coulter analyzers for simplified inventory
• Familiar user interface to reduce operator training
• DxLAB sample rack for efficient sample handling
• SimpleSolve onboard guidance for in-situ notifications and guided fixes

Operational performance

• Time to first result: from 8 minutes (chemistry) and about 18 minutes for selected immunoassays (example: βhCG)
• Throughput: up to 400 photometric chemistry tests/hour (up to 800/hour with ISE), up to 100 immunoassay tests/hour (one-step assays)
• Random access with priority sample handling and rapid response during testing surges
• One-tube testing for chemistry and immunoassay to reduce sample transfers

FlexMode operations

• Independent-side maintenance: run tests on one module while servicing the other
• Dynamic Sample Handler to prioritize immunoassay or chemistry based on sample urgency
• 12-lane sample handler with continuous loading for streamlined processing

Technical specifications

• Analytical method: Fully automated, random-access integrated system with chemistry and immunoassay modules
• Analytical principles: Spectrophotometry, potentiometry, chemiluminescence
• Assay types: Chemistry (endpoint, rate, fixed point, indirect ISE); Immunoassay (competitive, sandwich, antibody detection)
• Chemistry techniques: Colorimetry, turbidimetry, latex agglutination, indirect ISE; Immunoassay: paramagnetic bead-based methods
• Assay menu: >170 preprogrammed assays available
• Throughput details: 400 photometric tests/hour (up to 800 with ISE); 100 immunoassay tests/hour (one-step); ISE max 600 tests/hour; HbA1c max 65 tests/hour
• Sample types: Serum, plasma, urine, CSF, whole blood, amniotic fluid (assay dependent)
• Sample capacity: 168 tubes (24 racks × 7) with continuous loading; Chemistry STAT carousel 22 refrigerated samples; Immunoassay 60 samples in 6 carousel racks
• Barcoded reagents: automatic tracking of tests, expiration and lot numbers
• Supported container sizes: Tubes 13×75 mm, 13×100 mm, 16×100 mm; Sarstedt S‑Monovette 4.9/5.5/7.5 mL; cups and inserts including pediatric options; auto-aliquot supported
• Sample volumes: Chemistry 1.0–25 μL (0.1 μL increments); Immunoassay 10–110 μL
• Barcode symbologies: Codabar (NW-7), CODE 39, CODE 128, ISBT-128, Interleaved 2 of 5
• Compartment temperatures: chemistry reagent 4°C–12°C; cuvette 37°C ±0.3°C; immunoassay reagents 1°C–5°C; incubator ~36.4°C
• Reagent capacity: Chemistry 76 refrigerated positions (15/30/60 mL); Immunoassay 24 refrigerated positions
• Reaction vessels: Chemistry permanent glass cuvettes; Immunoassay disposable reaction vessels
• Sample quality checks: lipemia/hemolysis/icterus indices, clot detection, probe crash protection
• Calibration and QC: chemistry curves up to 90 days, immunoassay up to 63 days; Shewhart and multi-rule (Westgard) QC
• Dimensions & weight: approx. 650 kg dry weight; L 254 cm × H 124 cm (160 cm with monitor) × D 77 cm
• Clearance: rear 64 cm; left/right 50 cm; front 63.5 cm; top from chemistry top 124 cm
• Waste: chemistry drain max 10 m/height 1.5 m; immunoassay drain max 3 m/height 0.9 m; specified waste flow rates
• Water: max 20 L/hour, deionized CAP type II or better, bacteria-free, continuous flow
• Power: 200–240 V (50/60 Hz), 3.5 kVA
• Computer & display: 960 GB SSD, Windows 10, RS232/Ethernet LIS interfaces; 21.5" projected-capacitive touchscreen (1920×1080)
• Operating environment: 18°C–28°C, 20%–80% RH (no condensation), altitude ≤2,000 m, noise <75 dBA
• Communication: serial or TCP connection to LIS per ASTM protocol