Light/dark anxiety test animal research cage BX-BW

for micemodular

Comparison of anxiolytic drug-induced ease of exploratory activity between an illuminated compartment and a dark one: this test is a quick and evaluation of the animal anxious behavior and its modification by pharmacological agents, and available for rats and mice Numerous behavioural paradigms using several conflict procedures, social interaction or exploration of novel environments have been proposed as animal models of anxiety. B. Costall et al have described (Pharmacol. Biochem. Behav. 32(3): 777-785, 1989) a new model based on the adversive properties of the open field and in which anxiolytic drug-induced ease of exploratory activity is compared between an illuminated compartment and a dark one. Our dark-light (or Black & White) box allows easy and quick evaluation of the animal anxious behavior and its modification by pharmacological agents by assessing the animal displacements in two compartments with different size, color and illumination. It is a available for both rats and mice Operating principle The dark-light experimental box, constructed of Perspex, is composed of a small black compartments and a big white compartment separated by a connecting gate. Each compartment has its own removable Perspex floor of the same color of the respective walls and 90 X 90 mm sectors delimited by lines. The compartments are independently illuminated: the white one with a 100 W white bulb and the black one with a 40 W red bulb. Both bulbs are 370 mm from the floor of the box.