Paw pressure analgesiometer LE7306

Randall-Sellitofor preclinical researchfor animal research

Presentation
The Randall & Selitto test determines the nociceptive threshold in rodents by applying a uniformly increasing pressure to the paw. The LE7306 Rat Paw-Pressure system (BIOSEB) is designed for controlled, repeatable stimulation in preclinical pain research.

Operating principle
A step-motor drives a sliding support carrying a 1 mm conic tip mounted on an extensiometric load cell. The system provides a gradual, selectable pressure increase applied to the paw. Real-time force (grams) is displayed on the digital screen. The motor and tip are mounted on a pivoting stand to prevent excessive localized load. The Control Unit allows transducer adjustment, balance and reset, and selection of the step-motor speed. A remote foot-switch enables hands-free motor on/off control. At track end or upon pedal release the motor automatically reverses at higher speed to retract the tip.

Parameters Measured

• Force applied to the paw until withdrawal or vocalization (rats)
• Force applied to the tail until withdrawal (mice)
• Force applied to the paw until flexor toe response (mice)

Key features

• Digital display of current applied force (grams)
• Selectable pressure increase rate (adjustable motor speed)
• Pivoting support to avoid excess pressure on the paw
• Remote foot-switch for hands-free operation
• Optional data transfer software SEDACOM 2.0 for visualization and export

Technical specifications

• Reference: LE7306
• Model name: Rat Paw Pressure
• Conic tip diameter: 1 mm
• Force measurement: extensiometric load cell (display in grams)
• Actuation: step-motor with selectable speed / pressure increase rate
• Pivoting stand to prevent excess pressure on the paw
• Control Unit: transducer adjustment, balance, reset, motor speed selection
• Remote foot-switch for on/off control; automatic reverse at track end or pedal release
• Optional software: SEDACOM 2.0 for data visualization and export