BRAM-COR Cleaning in Place / Sterilizing in Place systems are designed to fully meet cGMPs requirements in cleaning and sterilizing practices commonly applied in pharmaceutical process lines.
C.I.P./S.I.P. Systems are supplied as fixed STATIONS or as MOBILE SKIDS, with manual, semiautomatic or automatic configuration.
C.I.P. systems can be equipped with different utilities for heating:
ELECTRICAL HEATER
HEAT EXCHANGER BY INDUSTRIAL STEAM
Each equipment is designed (in single or multitank configuration) to achieve the most effective and easily validable cleaning systems, starting from:
Type and size of equipment to wash
Required type of water and chemical agent
Pharmaceutical product to remove
Cleaning nozzles type
Washing sequence, automation level
In CIP/SIP automatic stations, CIP critical parameters integrate, are:
Contact time of solution
CIP supply temperature
CIP return temperature
Chemical conductivity for wash solutions
pH control
Final rinse resistivity
CIP solution flow rate
Supply pressure
Tanks levels
can be constantly monitored by the PLC and managed with cost-savings criteria. CIP/SIP System SW can be customized with different washing cycles.