An inaccurate endotoxin test result can not only halt your production, it can also put patients at risk. Accurate gel-clot assay results ensure the safety of your pharmaceuticals. The gel-clot endotoxin test is a simple qualitative method best used for low-volume laboratories or for products such as those that are highly viscous or extremely colorful. Our gel-clot endotoxin test lysate features a firm gel over a wide range of sensitivities as the buffered reagent provides better interference resistance and higher accuracy for routine LAL testing. Find out if this method is optimal for your lab.
As the original BET method of testing, a gel-clot endotoxin test is one of the simpler assays that can be conducted that yields qualitative results indicating the presence of endotoxins. This is determined through a clotting response and is a quick and effective way to detect harmful endotoxins for your injectable pharmaceuticals.
As part of our mission to provide scientifically sound and sustainable solutions, we've developed and optimized a robust, animal-free kinetic chromogenic rCR bacterial endotoxin detection assay curated to simulate the natural LAL reaction. Learn more about going animal-free.
How does the gel-clot endotoxin test work?
The gel-clot endotoxin test method displays the presence of endotoxins based on whether gel clot forms in the sample tube when introduced to the LAL reagent. If endotoxin is present in the sample, a gel clot will occur when in contact with the LAL reagent. If the clot stays at the bottom of the test tube after inverting it, the sample is positive for endotoxin.