Sensitive tumour detection and classification using plasma cell-free DNA methylomes
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Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA
Perform MeDIP (Methylated DNA Immunoprecipitation) followed by qPCR to estimate DNA methylation status of your sample using 5-methylcytosine antibody. Our kit contains high quality reagents to get the highest enrichment of methylated DNA with an optimized user-friendly protocol.
To perform an NGS compatible MeDIP-seq assay, you will need the MagMeDIP-seq Package.
Additionally, the development of Diagenode’s MagMeDIP qPCR Kit has been largely inspired by the reproducibility standards reached using the SX-8G IP-Star® Automated System. If you are interested in automating this protocol, please check our Auto MagMeDIP qPCR Kit.
Generate highly consistent results with internal controls in 24h
Minimize error with many reagents in 1 tube
Optimized purification (DIB - DNA isolation buffer)
Allows direct correlation between IP’d material & methylation status