Product OverviewThe AR-2000 radio-TLC imaging scanner provides direct digital counting of alpha, beta and gamma emitters on TLC plates, enabling quantitative radiochemical purity analysis and fast quality control of radiopharmaceuticals such as [18F]FDG. The system uses a gas-filled proportional counter offering a linear response over approximately 4–5 decades of activity, delivering a much wider dynamic range than X-ray film and supporting rapid, reproducible analyses. Full TLC lanes can be imaged in under one minute and multiple lanes processed automatically in a single run.
Key Features- Direct digital counting — measures positron, beta, gamma and alpha emitters without detector exchange
- Wide linear range — linear over ~4–5 decades, suitable for low- and high-activity samples
- Fast automated workflow — single-lane imaging < 1 min and unattended multi-lane runs
- Spatial resolution and sensitivity — configurable magnetic collimators for resolution/sensitivity trade-offs
- Software options — WinScan (standard) or optional RaPET-Lab/AR for GMP workflows
TechnologyThe detector is a gas-filled proportional counter capable of detecting low-energy betas (e.g., 3H), positron emitters (e.g., 18F, 11C) and gamma/alpha emitters. Direct digital counting ensures quantitative accuracy and reproducibility required for metabolism studies and radiochemical purity testing. The system supports programmable scanning and quick-change magnetic collimators to optimize performance for planar samples.
WinScan SoftwareWinScan provides instrument control and data acquisition for laboratories not requiring GMP-compliant software. Multi-slice acquisitions can be compiled into 2D image reconstructions for visual QC and documentation.
RaPET-Lab/AR software (optional)RaPET-Lab/AR is an optional workflow management package enabling automated execution of measurement, evaluation and quality-check procedures with integrated user management and unchangeable, audit-ready reports. It facilitates compliance with GMP, cGMP, GAMP 5 and 21 CFR Part 11 requirements.
Applications- PET / Nuclear Medicine QC — radiopharmaceutical purity and synthesis process control for isotopes such as 18F, 68Ga, 11C, 99mTc, 111In and therapeutic nuclides (e.g., 225Ac, 177Lu)
- Alpha-emitter TLC analysis — direct detection of alpha particles from isotopes like 225Ac, 211At and 223Ra
- Metabolite and radiotracer studies — quantitative analysis of 3H, 14C and positron-labeled compounds
- Lipid and biochemical separations — 1D/2D TLC analysis without scraping or transfer for rapid quantification
- Toxicology and tracer research — sensitive measurement of low-activity labelled compounds
Technical specifications- Model: AR-2000 radio-TLC imaging scanner
- Detector: gas-filled proportional counter (alpha/beta/gamma detection)
- Radioisotope coverage: positron emitters, low-energy betas (e.g., 3H), gamma and alpha emitters
- Quantitative linear range: approx. 4–5 decades of activity
- Imaging speed: single TLC lane imaged in < 1 minute; multi-lane automated runs supported
- Software: WinScan (standard); RaPET-Lab/AR (optional, GMP-capable, audit-ready reporting)
- Typical uses: radiopharmaceutical QC, FDG purity analysis, metabolite studies, radiotracer toxicology, lipid analyses, alpha-emitter TLC