HPLC chromatography detector

radioactivityPMT

Overview
The Flow-Count is a radioisotope HPLC detection system compatible with most liquid chromatography systems. It employs specially configured photomultiplier and/or PIN-diode detectors to identify gamma/positron and high-energy beta emitters across both high and low activity ranges. The system is particularly suited for PET tracer analysis of 18F and 11C.

Product status
Eckert & Ziegler has discontinued the Flow-Count; it has been replaced by FlowCountPRO. Service and maintenance support for existing Flow-Count units will continue to be provided.

Recent publications

• 2020 — White JM: Removal of Fc Glycans from [89Zr]Zr-DFO-Anti-CD8 Prevents Peripheral Depletion of CD8+ T Cells
• 2018 — Basuli F: Rapid synthesis of maleimide functionalized fluorine-18 labeled prosthetic group using "radio-fluorination on the Sep-Pak" method

Applications and compatibility

• Radiochemical analysis and quality control of PET tracers (18F, 11C)
• Integration with HPLC systems in radiochemistry and radiopharmacy laboratories
• Detection of gamma, positron and high-energy beta emissions across a wide activity range

Technical specifications

• Type: Radioisotope HPLC detection system
• Detectors: Specially configured photomultiplier and/or PIN-diode detectors
• Compatibility: Compatible with most liquid chromatography systems
• Detected emissions: Gamma/positron and high-energy beta emitters
• Activity range: Detects both high and low activity levels
• Primary applications: PET tracer analysis (18F and 11C)
• Status: Discontinued; successor: FlowCountPRO

Service & maintenance
Eckert & Ziegler continues to offer service, spare parts and technical support for installed Flow-Count systems.