A high degree of automation and flexibility is offered by the new half-automated on-/offline dissolution system. It is controlled via the fully validated ERWEKA Disso.net software and offers automated dissolution testing, integrated UV-Vis analysis and sample collection iinto HPLC vials or glass tubes for reference samples or later HPLC analysis.
The ERWEKA on-/offline dissolution system offers the possibility to include a UV/Vis spectrophotometer (ERWEKA, Perkin Elmer, Shimadzu, Analytic Jena, Agilent) into the sample withdrawal system.
Therefore the ERWEKA on-/offline dissolution system can be used as:
sample collection device (max. 324 samples; incl. sample tempering), and
an UV-VIS online system (incl. virtual dilution by various path length with optimized flow-through cuvettes).
An automated system runs without user observation. In order to determinate the cause in case of unexpected results, ERWEKA offers a video recording system where six dissolution vessels are monitored. The video system allows recording of each test-run in combination with real-time overlapping dissolution profile to identify disturbances such as coning etc. and to get the visual impression of 24 hours in 2 minutes. The video monitoring is a very powerful tool for method development as well for troubleshooting.