Research assay kit PreCursor-M+

clinical

Qualitative detection of promotor hyper methylation levels of 2 cervical cancer associated tumor suppressor genes (FAM19A4 and hsa-miR124-2). Identify HPV positive women with high short-term progression to (pre)cancer. Special Features: Sample types: - Bisulfite-converted DNA isolated from physician collected cervical specimens or self-collected vaginal specimens Clinical performance - Long-term data: - Most evaluated and validated methylation assay to identify HPV positive women with progressing cervical disease in direct need for colposcopy or other follow-up procedures1,2 - Demonstrating very high sensitivity for cervical cancer detection (95.0%) in HPV-positive cervical specimens - Longitudinal data: The long-term risk for cancer with a negative PreCursor-M+ is lower than with a negative cytology result; for CIN3 the long-term risk is similar as cytology3,4 Flexible: - Suitable for different sample types, including self-samples and common Liquid Based Cytology media types - Compatible with standard DNA extraction methods Reliable: - Build-in check for sample quality ensuring reliable results Precursor-M+ is a registered trademark of the legal manufacturer, Self-screen B.V., the Netherlands, and is distributed by Fujirebio Europe.