The SaberVet Feline Infectious Peritonitis Virus Antibody Rapid Test sold by Antigenne is a lateral flow immunoassay intended for the qualitative detection of specific antibody from feline infectious peritonitis virus (FIPV) in feline ascites, serum, plasma or whole blood samples. The test is useful for determination of FIPV infection.It is recommended for cats with symptoms of significantly enlarged abdominal circumference.
Description
Feline Infectious Peritonitis (FIP) is a fatal disease caused by certain mutant strains of feline coronavirus (FCoV).The pathology of FIP can be characterized according to its two main forms- -wet (exudative type) and dry (non-exudative type)
Wet FIP (exudative type)
Wet FIP is characterized by the accumulation of fluid in body cavities, usually in the abdominal and thoracic cavities. These effusions are usually:
Yellow to clear fluid that may be viscous.
High protein content (total protein concentration usually greater than 3.5 g/dL).
Low cellular content, with neutrophils and macrophages predominating.
Pathologic features
Vasculitis: wet FIP often presents with perivascular inflammation called necrotizing vasculitis. The walls of the blood vessels are eroded, leading to accumulation of exudate.
Plasma membrane inflammation: the peritoneum, pleura, and pericardium often show inflammation in the form of fibrin deposition and inflammatory cell infiltration.
Dry FIP (non-exudative type)
Dry FIP is characterized by granulomatous lesions of multiple tissues and organs rather than body cavity fluid collection. These granulomas are found primarily in: Liver, kidneys, lymph nodes, spleen, CNS