• The measurement of spontaneous and voluntary activity
• The identification of the animal who goes into the activity wheel
In collaboration with a Swiss laboratory, we developed this cage, equipped with an activity wheel to measure the spontaneous and voluntary activity of an individual within a group research team’s desire being to maintain social ties.
The animals are identified with our TAM transponders. The built-in card reader in the wheel reads the animal’s chip as it goes into the wheel and operates it. The software records its activity and its identification number.
Free and unconstrained, these measures do not induce stress to the animal.
Many activity parameters according to environmental and/or chemical factors are recorded:
• The number of entries in the wheel (without travel made)
• The pace of activity with the number of laps completed
• The direction of travel (clockwise, counterclockwise)
• The distance traveled in both directions
• The total time spent in the wheel
These paradigms are particularly useful for:
• The study of the rhythms of activity and their deregulations,
• The study of circadian rhythms,
• The study of aging,
• Studies on anxiety and depression,
• The time screening of all development-related models (pre- and postnatal
environments, inducible KO, lesions…)
• Pharmacological studies (measurements before and after treatment).
The activity wheel with an XXL cage, in addition to ensuring social cohesion, ensures the
maintaining and improving of the rodent’s physical condition with regular activity. It helps to
control body weight.