Solution reagent kit A-R0200000601

blood samplefor clinical chemistrygamma-GT

Product for use in the quantitative determination in vitro of the Creatinine concentration in human serum or urine. The results of the test must always be interpreted in conjunction with the clinical context. For professional use only. CLINICAL SIGNIFICANCE Although -GT IFCC is present in a large number of tissues, the enzyme which we wish to detect in the serum is principally part of the hepato-biliary system. Consequently, raised levels of -GT are seen in all forms of disease or damage to the hepatic system. From the clinical viewpoint, the enzyme is useful for the diagnosis of obstructive jaundice, cholangitis and cholecystitis. High -GT levels are also seen during the assumption of alcohol or pharmaceutical products (sedatives, anticonvulsants and tranquillizers). PRINCIPLE Gamma glutamyl transpeptidase (y-GT) catalyzes the transfer of the g-glutamyl group from the substrate g-glutamyl-3-carboxy-4-nitroanilide to glycylglycine releasing Lglutamyl-glycylglycine and 5-amino-2-nitrobenzoato.