The LC-4000 Series RHPLC system with maximum operating pressure 700bar, 70MPa) has been designed to future-proof your HPLC requirements. The system can be used with conventional 3 – 5 μm particle size analytical columns at typical lower pressures around 10 to 20 MPa (1500 to 3000 psi) and can also be used with smaller particles such as shorter length UHPLC columns and superficially porous (SPP) or Coreshell that require slightly higher pressure solvent delivery to provide optimum linear velocity through the column.