Gravimetric filter C850M

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The C850M Integrated Water Insoluble Matter Testing System is a gravimetric-method instrument for detection of water-insoluble matter in chemical reagents and pharmaceutical excipients. It automates sample filtration, drying, cooling and precise weighing to produce traceable gravimetric results suitable for GMP environments.

Overview / Testing principle
The sample is dissolved in water, insoluble matter is separated by filtration and washed. After controlled drying and cooling, the insoluble residue is weighed to determine water-insoluble matter content by gravimetric calculation.

Applications

• Chemical reagents: determination of water-insoluble matter in various laboratory and industrial reagents.
• Pharmaceutical excipients: determination of water-insoluble matter in excipients used in drug formulations.

Characteristics

• Traceable data: automated gripper handles and moves 12 test cups for rapid sequential weighing; dual-chamber design separates evaporation and weighing to protect the balance from high temperature and humidity.
• High-precision weighing: standard electronic balance with 0.1 mg resolution and optional higher-precision balances (repeatability down to 0.05 mg or 0.01 mg resolution); balance visible through viewing panel and calibratable with standard weights.
• Safe & compliant: fully closed, zero-leakage water bath to prevent gas escape; automatic filter-residue cleaning and drainage; rapid liquid cooling for room-temperature weighing; nitrogen purge cycling and independent electrical control; condensation recovery to reduce environmental impact.
• Intelligent control & software: 10.1-inch medical-grade touch-screen interface (instrument operable without PC); space-saving desktop mainframe; automated washing, drying, cooling and weighing cycles; sensors with audible/visual alerts; network port for remote control and upgrades; professional software meeting GMP requirements with multi-level user management and optional 21 CFR Part 11 electronic signature support.

Test standard compliance
Complies with GB/T 9738 and other relevant standards for testing water-insoluble matter in chemical reagents and pharmaceutical excipients.

Technical specifications

• Model: C850M.
• Test stations: 12 test positions.
• Test range (mg): standard 0.3–80,000 mg; optional 0.05–10,000 mg.
• Resolution (mg): standard 0.1 mg; optional 0.01 mg.
• Repeatability (mg): standard ±0.3 mg; optional ±0.05 mg.
• Temperature range: room temperature to 130 °C.
• Temperature fluctuation: ±0.5 °C.
• Glass filter crucible volume: 100 mL (customizable).
• Glass filter crucible pore size: 5 μm – 15 μm (customizable).
• Gas specification: compressed air (user-supplied); required pressure ≥ 72.5 PSI / 500 kPa; port size: Φ8 mm polyurethane tube.
• Instrument dimensions (mainframe): 24.8” H × 41.3” W × 28.7” D (63 cm × 105 cm × 73 cm).
• Power supply: 120 VAC ±10% 60 Hz or 220 VAC ±10% 50 Hz.
• Net weight: 396 lbs (180 kg).
• Standard configuration: mainframe including balance (0.1 mg), electrical control module, reagent collection module, liquid cooling module, 12 glass filter crucibles, Φ8 mm polyurethane tube.
• Optional parts/functions: GMP-compliant software and PC system, 21 CFR Part 11 support, air compressor (exhaust > 200 L/min), 100 mL glass filter crucibles, higher-precision balance (0.01 mg), calibration weight (50 g).