Solubility testing system C850H

chemicalInsoluble matter in waterfor medical devices

The C850H Integrated Water Insoluble Matter Testing System is a gravimetric-method analyzer designed to detect water insoluble matter in chemical reagents and pharmaceutical excipients. It automates filtration, drying, cooling and weighing workflows to provide traceable, GMP-ready results for laboratory and production quality control.

Characteristics

• Traceable Data
  • Fully automatic gripper capable of rapidly moving and weighing 25 test cups.
  • Dual‑chamber design separates evaporation and weighing to isolate the scale from high temperature and humidity.
  • High‑precision electronic balance with visible display; designed for straightforward calibration and maintenance to ensure data traceability.
• Safe & Compliant
  • Fully closed, zero‑leakage water bath to prevent harmful gas escape.
  • Automatic filter residue cleaning and drainage system.
  • Rapid liquid cooling to enable room‑temperature weighing in minimal time.
  • Nitrogen purge cycling and independent electrical control for enhanced safety.
  • Condensation recovery system to reduce environmental discharge.
• Intelligent Control
  • 12.1" medical‑grade touch screen interface for standalone operation.
  • Desktop mainframe design to save laboratory bench space.
  • Automated sequence covering washing, drying, cooling and room‑temperature weighing.
  • Integrated sensors with audible and visual alarms to support operator safety.
  • Network port for remote control and firmware updates; professional software supporting GMP data traceability, multi‑level user rights and electronic signatures (21 CFR Part 11).

Testing Principle
The sample is dissolved in water and insoluble matter is filtered out; the residue is washed, dried and the weight of insoluble matter is determined by the balance.

Applications

• Basic Applications
  • Chemical Reagents: Determination of water insoluble matter in various chemical reagents.
  • Pharmaceutical Excipients: Determination of water insoluble matter in various pharmaceutical excipients.

Technical specifications

• Model: C850H
• Test range (mg): 0.05 – 10,000 (optional 0.3 – 80,000)
• Resolution (mg): 0.01 (optional 0.1)
• Repeatability (mg): ±0.05 (optional ±0.3)
• Temperature range: Room temperature – 130 °C
• Temperature fluctuation: ±0.5 °C
• Test stations: 25
• Glass filter crucible volume: 100 mL (customizable)
• Glass filter crucible pore size: 5 µm – 15 µm (customizable)
• Gas specifications: Compressed air (gas source provided by user)
• Gas source pressure: ≥ 72.5 PSI / 500 kPa
• Port size: Φ8 mm polyurethane tube
• Instrument mainframe dimensions: 32.6” H × 43.3” W × 28.7” D (83 cm × 110 cm × 73 cm)
• Power supply: 120 VAC ±10% 60 Hz or 220 VAC ±10% 50 Hz (choose one)
• Net weight: 440 lbs (200 kg)
• Standard configuration: Instrument mainframe including balance (0.01 mg), electrical control module, reagent collection module, liquid cooling module, 25 glass filter crucibles, Φ8 mm polyurethane tube
• Optional parts/functions: GMP software and computer system (21 CFR Part 11), air compressor (exhaust > 200 L/min), additional 100 mL glass filter crucibles, alternative balance (0.1 mg), calibration weight (50 g)