With THUNDER Imagers you begin every experiment with confidence. They are your solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids.
THUNDER Imagers feature innovative Leica technology Computational Clearing. It efficiently removes out-of-focus blur in real time, enabling the meaningful use of 3D specimens with camera-based fluorescence microscopes.
The high sensitivity of the system ensures low phototoxicity for physiologically relevant data sets. THUNDER systems offer a range of tools that assist you throughout your workflow from set up to data analysis.
Multi position experiments: tracking cell changes
THUNDER Imager Cell offers both speed and reliability for your 3D cell culture multiwell experiments. For example, when tracking development of organoids, the system's speed and reliability allows you to obtain excellent results.
Accurate multi-position time-lapse experiments are aided by:
Reliable focus drift correction with the Adaptive Focus Control (AFC)
Software autofocus that compensates for changes in specimen position
Reproducible Z-positioning with a precision of up to 20 nm (closed-loop focus)
The hardware triggered Quantum Stage moves rapidly and accurately to all positions with excellent repeatability (< ±0.25 µm).
Image at the speed of life – Cellular processes
Live cells contain a range of dynamic processes that require a system that can capture data with high temporal resolutions.
THUNDER Imagers only require a single fluorescence image to produce deblurred data. With THUNDER, you are only limited by the speed of your camera.