Free T3 EIA Test Kit
An enzyme immunoassay (EIA) for the in vitro quantitative detection of Free T3 (Triiodothyronine) in human serum.
The Free T3 EIA Test Kit is an enzyme immunoassay for the in vitro quantitative detection of Free T3 (Triiodothyronine) in human serum.
3,5,3’ Triiodothyronine (T3) is a thyroid hormone with a molecular weight of 651 daltons.1 About 20 percent of the body's T3 comes from the synthesis of T3 within the thyroid while the rest is derived by deiodination of the other thyroid hormone thyroxine (T4) which occurs in the peripheral tissues.2,3 Although T3 is present in less concentration than T4, it is more rapid and biologically active. T3 is bound to thyroxine binding globulin (TBG), prealbumin and albumin in blood. Approximately 0.3% is present unbound or free T3 and represents the physiologically active thyroid hormone. While Total T3 concentrations are dependent on thyroid status, peripheral conversion of T4 to T3, or on the level of TBG during many clinical conditions such as pregnancy and administration of oral contraceptives, Free T4 is less sensitive and remains constant. Therefore, free T3 may provide better indication of thyroid status. Measurement of Free T3 is generally recommended for hyperthyroidism found in Graves’ disease and toxic adenomas. 4,5 The Free T3 EIA Test Kit is an immunoassay for the quantitative detection of the presence of Free T3 (Triiodothyronine) in serum specimen. The test utilizes monoclonal antibodies to selectively detect Free T3 in serum.