R821 tricolor multichannel fiber photometry system is compatible with optoelectronics equipment. It has different wavelengths of excited light, 410nm, 470nm or 560nm, of which 410 is used to acquire reference signal and eliminate noise. The system can record signal of green fluorescence indicator like GCaMP and dLight or neurotransmitter probe and red fluorescence indicator like RCaMP, jrGECO1a or neurotransmitter probe.
And also it can be applied to record the neural signal for 9 sites at the same time.
Overview
The fiber photometry system records changes in the fluorescence intensity of neurons in a specific brain area to reflect neuronal population activity. In the study of neural circuits, the fiber photometry system can perform long-term stable monitoring of the neurons of freely moving animals, and explore the correlation between neural activity and animal behavior.
Main Applications:
Ca2 + and neurotransmitter signal detection
Study the function of neural circuits
Explore the mechanisms of neurological diseases
Develop new fluorescent sensor probe
Experiment of optical principle
Advantages
Three kinds of excitation light sources, that is 410nm、470nm and 560nm, are respectively used for excitation of reference, green fluorescence and red fluorescence;
Support up to 9 channels, suitable for simultaneous experiment of multiple animals or multiple brain locations;
Dual highly sensitive detectors enabling independent and sequential detection to avoid interference of fluorescence excitation and detection, acquiring more accurate signal;