Amplifex Keto Reagent is designed specifically to enhance signal strength up to 500-fold (depending on the analyte).
The Amplifex Keto Reagent is a universal reagent that reacts with a molecule's keto or aldehyde functional group, such as the ketone in ketosteroids (e.g., testosterone).
With the Amplifex Keto Reagent, your sample size can be dramatically reduced, while still achieving LLOD and LLOQ levels that were difficult, if not impossible, by mass spectrometry analysis even on the most-sensitive platforms.
Intelligent design boosts ionization efficiency and improves fragmentation
Substantial reduction in sample volume and analysis time is enabled.
Reactions are simple (one-step derivatization) and fast (30-60 minutes).
Universal derivatization technique reacts with all molecules containing the keto or aldehyde functional groups
Designed specifically to enhance sensitivity of trace analytes and enable workflows that push the limits of sample volume
Amplifex Keto is a customized derivatizing reagent designed to react specifically with a molecule's keto and aldehyde functional groups to improve ionization efficiency. (i.e. Amplifex™ Keto Reagent treatment results in a sensitivity enhancement of ~40-fold in testosterone and universally reacts with all ketosteroids across an array of sources (plasma, dried blood spot, dialyzed samples, urine, and oral fluids).