Rapid quality control test SC-1019-40

cotininefor nicotineurine

SCREEN TEST NICOTINA Cotinine Rapid Test Panel REF: SC-1019-40 Quick test for quality identification of cotinine (nicotine metabolite) via urine. Only for the determination of smoker status. Not thought for medical diagnostic use. The COT rapid test is a quick chromatographic immunological test for cotinine detection. Also available in the version via saliva (Nicotine-s Screen Test Product code: SC-1026-25). Cotinine is the first degree metabolite of nicotine, a toxic alkaloid that causes the stimulation of autonomous ganglia and central nervous system in humans. In Addition to Tobacco, Nicotine Is Also Available On The Market As An Active Ingredient of Smoke Replacement Therapies Such As Tires, Transdermal Patches and Nicotine Nasal Sprays. In a 24-hour urine, it is excreted about 5% of a nicotine dose as a drug unchanged with a 10% in the form of cotinine and 35% as a hydroxicinine; It is believed that the concentrations of other metabolites interested less than 5%. While it is thought that cotinine is an idle metabolite, its elimination profile is more stable than that of nicotine, which depends a lot on the pH of urine. The result that cotinine is considered a good organic marker in determining the use of nicotine. The plasma half-life of nicotine is about 60 minutes following inhalation or parenteral administration. Nicotine and cotinine are rapidly eliminated by the kidneys; The cotinine identification window in the urine at a threshold-limit level of 200 ng/ml is around 2-3 days after the use of nicotine. The COT rapid test (urine) is a quick urine screening test that can be performed without the use of instrumentation.