Healthcare facility imager

infusionblood flowlaser speckle contrast

An advanced imaging technology based on dynamic laser speckle analysis, specifically designed for animal experiments and clinical research. It enables real-time, non-invasive monitoring of microcirculatory blood flow dynamics in living tissues, providing a precise visualization tool for cardiovascular disease research, drug efficacy evaluation, neuroscience, wound healing, and other fields. Principle: When a target is illuminated by a laser beam, the reflected light forms a random interference pattern (composed of bright and dark areas), known as a laser speckle pattern. If the target is stationary, the speckle pattern remains unchanged. However, movement of the target—such as red blood cell motion in tissues—causes fluctuations in the speckle pattern. The rate of speckle variation depends on the velocity of the moving target within the monitored area: faster movement results in more pronounced speckle changes. This variation is quantified as speckle contrast, which correlates with blood flow velocity. This principle forms the basis for assessing blood perfusion using laser speckle technology. By analyzing microcirculatory blood flow parameters, the system evaluates vascular structure, microcirculatory function, and metabolic activity. It enables research into pathological mechanisms and microcirculatory changes during ischemia, hypoxia, stroke, inflammation, edema, hemorrhage, allergies, shock, tumors, burns, frostbite, and radiation damage. Dynamic Speckle Algorithm Optimization Ultra-Sensitive CMOS Sensor Thermal-Controlled Laser Safety Rapid Auto-Focus & Precision Electric Focus Optical Lens Array