Coronary stent Helios®

metalcobalt-chromiumtitanium

Helios® Sirolimus-eluting Coronary Stent with Biodegradable Polymer Technology Excellent delivery system Cobalt-chromium alloy Titanium oxide coating Sirolimus Fully biodegradable PLGA drug-controlled release coating Titanium-oxide coating Rutile structure: a long-term stable presence on the surface of the stent. Hemocompatibility: antithrombotic effect – reduces platelet and fibrinogen adhesion and activation. Tissue compatibility: inhibits inflammatory response, restores endothelial cell structure and function, and reduces metal ion release. Titanium-oxide coating: 10-30nm. PLGA: Thickness of lumen side 9-13μm, Thickness of wall side 15-19μm. Co/Cr STRUT: Thickness 80μm. Sirolimus: 135μg/cm2. Good biocompatibility makes perfect vascular endothelialization Titanium-oxide coated stent animal experiment report Scanning of electron microscopy Two weeks after stent implantation, most of the titanium-oxide coated stent was basically covered by endothelium, while a large area of the non-titanium-oxide coated stent was not. At 12 weeks of stent implantation, the endothelial cells on the titanium-oxide coated stent were elongated with a smooth surface, and regularly arranged along the long axis of the cells. The shape of the endothelial cells on the non-coated stent was oval with a large number of bumps on the surface, indicating that the endothelial cells on the stent with coating matured quickly and completed endothelial coverage and endothelial maturation rapidly.