Automatic molecular imaging system iMScope™ QT

laboratoryfor researchfor biomolecular imaging

Overview
Next-generation mass spectrometry imaging solution from Shimadzu: the iMScope QT integrates an optical microscope with a Q-TOF mass spectrometer to enable correlated morphological and molecular analysis. The system delivers spatially resolved MS imaging with fast data acquisition and sensitive detection to support advanced research workflows.

Total System for MS Imaging Analysis
Mass spectrometry imaging is executed in three principal steps:

• Pretreatment
• Data acquisition
• Data analysis

Optimizing each step accelerates time-to-result and enhances data reliability for laboratory and research environments.

Key Points for MS Imaging
Integrated fusion of MS images and optical microscope observations to correlate morphology and molecular distribution; design focused on combining speed, sensitivity and spatial resolution; end-to-end workflows for reproducible sample-to-result processing.

Features

• Combined Analysis: Fusion of MS images with optical microscope observations enables direct correlation of molecular distributions with tissue or sample morphology.
• Quantification and Spatial Distribution: Acquire qualitative and quantitative LC-MS data together with spatial position information from MS imaging using a single integrated instrument.
• Q-TOF Compatibility and Imaging Performance: Q-TOF (LCMS-Q-TOF) compatibility for accurate mass measurement, enabling high-resolution, high-speed image acquisition and streamlined data analysis workflows.

Videos

• Mass Spectrometry Imaging: Paving the Way for the Next Generation
• iMScope QT Introduction to tissue sample analysis

Downloads (selected)

• iMScope QT - Imaging Mass Microscope (product brochure)

Applications (documents table)
Documents | Creation Date
Analysis of Citrate Distribution in Plant Tissues Using Multimodal Imaging | 2026-03-26
Analysis of C=C Positions of Lipids in Mouse Brain Sections Using MALDI-OAD-MS/MS | 2026-03-10
Multidirectional Analysis of Plant Alkaloids Using MS Imaging and OAD-TOF System | 2026-03-10

Trademark
iMScope is a trademark of Shimadzu Corporation.

Technical specifications

• Product type: Imaging Mass Microscope
• Model name: iMScope QT
• Brand: Shimadzu
• Integrated optical microscope with mass spectrometer for combined morphology and MS imaging
• Mass analyzer: Q-TOF (LCMS-Q-TOF) compatibility
• Key capabilities: spatially resolved MS imaging, fast data acquisition, high sensitivity
• Complete workflow: sample pretreatment, data acquisition, data analysis
• Available resources: product brochure and application notes (see downloads and applications)