Mass spectrometer MALDI-8020

time-of-flightfor proteomicsfor nucleic acid quantification

Overview
The Shimadzu MALDI-8020 is a benchtop linear MALDI-TOF mass spectrometer engineered for high-performance mass measurement in space-constrained laboratories. It supports rapid mass analysis of peptides, proteins, polymers and oligonucleotides and is intended for research use only (not for diagnostic procedures).

Key features

• Linear mode (positive ion) MALDI-TOF
• 200 Hz solid-state laser, 355 nm
• Load-lock chamber for fast sample introduction
• UV laser-based source cleaning (patented) with TrueClean™ automated source cleaning
• Compact benchtop footprint
• Quiet operation (<55 dB)

Feature details

• Sample targets: Compatible with FlexiMass™ microscope slide-format targets to match different workflows.
• TrueClean™ automated source cleaning: Preserves performance and reduces downtime; combined with wide-bore ion optics to minimise source contamination.
• Data management & compliance: Operates under MALDI Solutions™ software with a centralized Microsoft® SQL database to store sample lists, parameter sets and acquired data; facilitates 21 CFR Part 11 workflows.
• Quality: Designed and manufactured to ISO 9001:2015 standards for laboratories developing MALDI-based methods.

Performance example
Example: a 4.2 kDa peptide measured with an average resolution >5000 FWHM (resolution reported by instrument software).

Applications (selected documents)
O-Antigen Typing of Escherichia coli by MALDI-TOF MS Analysis of O-Antigen Polysaccharides — 2026-05-26
SpheriCal Calibrants on the MALDI-8020. High Purity, Monodisperse Calibrants Suitable for a Range of Applications — 2026-02-17
Amino Acid Sequence Analysis of Peptides Containing Modified Amino Acids Using The PPSQ-50 Gradient System — 2025-06-10

Downloads (selected brochures)

• MALDI-8020 - Benchtop Linear MALDI-TOF Mass Spectrometer (PDF, 1.39MB)
• Oligonucleotide Therapeutics Solution Guide (PDF, 6.95MB)
• MALDI EasyCare (PDF, 2.27MB)

Videos (examples)
Product videos demonstrate loading, operation and applications of the MALDI-8020, including titles such as "MALDI-8020 Loading and Operation" and "MALDI 8020 Benchtop Linear MALDI-TOF Mass Spectrometer".

Notes
For Research Use Only. Not for use in diagnostic procedures.

Technical specifications

• Model: MALDI-8020
• Instrument type: Benchtop linear MALDI-TOF mass spectrometer (positive ion, linear mode)
• Laser: 200 Hz solid-state laser, 355 nm
• Sample introduction: Load-lock chamber for fast sample introduction
• Source cleaning: UV laser-based source cleaning (patented); TrueClean™ automated source cleaning
• Ion optics: Wide-bore ion optics to minimise source contamination
• Acoustic level: <55 dB (quiet operation)
• Resolution example: >5000 FWHM for a 4.2 kDa peptide (software-calculated)
• Sample formats: Compatible with FlexiMass™ microscope slide-format sample targets
• Software & data management: MALDI Solutions™ software; centralized Microsoft® SQL database; supports compliance workflows (facilitates 21 CFR Part 11)
• Quality standard: Designed/manufactured to ISO 9001:2015
• Intended use: For Research Use Only. Not for diagnostic procedures.