Breathing simulator BRS

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The automated features of the Breathing Simulator (BRS) series calculate duration, frequency and I:E ratio and are an important component for IVIVC testing. Product Details The Breathing Simulator (BRS) family of products was originally designed around the nebulizer requirement to test under tidal breathing. Today, BRS products are increasingly being used to replace constant flow rate (square wave) conditions to more closely represent conditions in vivo and simulate breathing patterns for inhaler testing. Unlike the traditional ventilator simulator systems, the BRS series was specifically designed to meet USP and specifications, automating the critical calculations of duration, frequency of breath, I:E ratio, etc. Our suite of products is designed specifically for each individual application in OINDP testing. The upper end models have very flexible computer-controlled breath profiles, ultimately enabling the next wave of IVIVC testing. Explore the possibilities for enhanced IVIVCs and precise testing across sensitive OINDP scenarios. Available Models BRS 100i: generates breathing patterns for nebuliser and inhaler testing per ISO 27427:2013 and USP . BRS 200i: simulates breathing profiles for testing nebulisers and MDIs with spacers/VHCs per Ph. Eur. and USP standards. BRS 300i: offers 0 mL–5 L volume, ideal for MDI/DPI testing with up to 240 L/min flow rate. Applications Dry powder inhalers (DPI) Metered dose inhalers (MDI) Nasal spray, aerosol, powder Nebulizers Features and Benefits Creates a range of breathing profiles and tidal patterns for USP 1601, 1602 breathing profiles