AStudies have shown that B-raf gene mutation exists in a variety of malignant tumors such as non-small cell lung cancer and colorectal cancer. Among them, V600E point mutation on exon 15 is the most common, accounting for more than 90%. This mutation leads to abnormal activation of B-raf protein, which leads to the failure of treatment of patients to receive EGFR-TKI drugs and EGFR monotherapy.
Based on the real-time fluorescent PCR platform, Tianlong Human B-raf Gene V600E Mutation Detection Kit is used to detect B-raf gene V600E mutation by combining alleles specific amplification (ARMS) technology, wild-type gene amplification inhibition technology and multiple PCR technologies. The test result of this kit can assist the clinician in developing drug regimens for patients with non-small cell lung cancer and colorectal cancer.Get A Quote
Features
High sensitivity: Reliable detection of V600E mutations in the B-raf gene, sensitive to detect up to 1% mutation in B-raf gene
Internal Control: The use of internal control system in the kit can effectively prevent false negative results
High Precision: The precision values of intra and inter Ct values are all ≤5%
User-friendly: Widely applicable in instruments with FAM, ROX/Texas Red fluorescence channels
More Accessible: CE marked, accessible for more counties