Lung cancer assay kit P112H

colorectal canceroncologyfor genes

K-ras gene, located on chromosome 12p12.1, is one of the important oncogenes. Studies have shown that K-ras gene mutations exist in non-small cell lung cancer and colorectal cancer, and mutation of K-ras occurring at codon 12 and 13 which could cause KRAS protein to mutate and remain activated can render the drug ineffective. The kit uses genomic DNA extracted from tumor paraffin-embedded tissue sections of human non-small cell lung cancer and colorectal cancer as test samples for the qualitative detection of 12 somatic mutations at codon 12 and 13 of K-ras gene. This product is suitable for patients with non-small cell lung cancer and colorectal cancer before entering the individualized targeted therapy course and provides auxiliary diagnostic evidence for the individualized medication of clinical tumor-targeted drugs. Features Wide Coverage: Reliable detection of Human K-ras gene Mutation, covering 12 somatic mutations at codon 12 and 13 of K-ras gene in a single run High Sensitivity: Sensitive to detect up to 1% mutation in K-raf gene Internal Control: The use of internal control system in the kit can effectively prevent false negative results High Precision: The Tm coefficient of variation was no more than 8% or Tm value difference ≤1℃ More Accessible: CE marked, accessible for more counties User-friendly: Validated on the most common qPCR machines with FAM fluorescence channel