Solution reagent KD-HMM-0015

for researchfor PCRblood sample

Product Details
Product name: Cell-free DNA Extraction Kit (cfDNA)
Catalog No.: KD-HMM-0015
Pack size: 4 mL sample system; 50 rxns
Storage: 2–8°C
Shelf life: 2 years
Certification: FDA

Features

• High yield: optimized protocol for improved recovery of short cfDNA fragments; plasma standard sample recovery > 85%
• High purity: optimized buffer system to remove PCR inhibitors and protein contaminants
• Low elution volume: elution possible down to 20 µL for higher nucleic acid concentration
• Flexible input volume: supports extraction from 0.2–5 mL serum/plasma (scalable workflows optimized for 1–10 mL plasma)

Product Introduction
Cell-free DNA (cfDNA) are short, fragmented DNA molecules circulating in body fluids released from apoptotic and necrotic cells. Analysis of cfDNA — notably circulating tumor DNA (ctDNA) from plasma — is widely used in non-invasive diagnostics in oncology, prenatal testing and transplant monitoring. This kit is optimized to capture low-abundance, short cfDNA fragments from large-volume liquid samples while minimizing contamination from genomic DNA derived from lysed blood cells.

Product Application

• Liquid biopsy for cancer detection, therapy monitoring and minimal residual disease (MRD) assessment
• Non-invasive prenatal testing (NIPT) for fetal chromosomal aneuploidies
• Monitoring of organ transplant rejection (donor-derived cfDNA)
• Research on cfDNA biology in sepsis, trauma and autoimmune conditions

Product Advantages

• Sensitive recovery of low-concentration, short-fragment cfDNA
• Effective removal of common plasma PCR inhibitors (heparin, EDTA, hemoglobin) and contaminants
• Scalable processing to concentrate cfDNA from variable or large plasma input volumes
• NGS-ready output: eluted cfDNA of high purity compatible with downstream library preparation and sequencing

Technical Specifications

• Catalog number: KD-HMM-0015
• Commercial name: Cell-free DNA Extraction Kit
• Pack size: 4 mL sample system; 50 rxns
• Intended input volume: supports ~0.2–5 mL serum/plasma (optimized for 1–10 mL plasma for concentration workflows)
• Typical recovery rate (plasma standard sample): > 85%
• Minimum elution volume: as low as 20 µL
• Storage conditions: 2–8°C
• Shelf life: 2 years
• Certifications: FDA