ammonia POC reader / for gastrointestinal infections / Helicobacter pylori / urease
HELIC ABT

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Characteristics

  • Applications:

    for gastrointestinal infections

  • Tested parameter:

    ammonia, Helicobacter pylori, urease

  • Sample type:

    breath

  • Analysis mode:

    biochemical

Description

HELIC ABT Reader – is an innovative automatic testing device, a ready-to-use test for qualitative detection of Helicobacter pylori (H.pylori) urease activity among patients with suspected H.pylori infection with high accuracy and without the involvement of the laboratory.

Principle of Operation
During the patient examination two air samples are selected: before and after taking a portion of unlabelled urea 12C. If the patient is infected with Helicobacter pylori, after taking a portion of unlabelled urea 12C, the ammonia in the mouth cavity air will increase and the indicator composition in the tube will change its color from yellow to blue. The device reads and compares the color change, after that gives the result.

Description of the method

HELIC Ammonia Breath Test (HELIC ABT) was designed to exclude pain and discomfort during the diagnostic procedure. HELIC ABT is applied by gastroenterologists, general practitioners, by staff of primary health centers and dispensaries and allows to implement Near Patient Testings (NPT) in any place and situation. No samples need to be sent to a central laboratory.
This is the biochemical method is based on produces a large amount of urease. H.pylori produces a large amount of urease, which degrades urea to ammonia (NH4+). HELIC ABT uses kinetic registration of ammonia concentration in patient’s breath air before and after a portion of unlabelled urea 12C is taken. The value of ammonia level is expressed in color change of indicator composition inside the tube.