Medical software BIO-DWB2-POSTUR

laboratoryanalysisinner ear

Presentation
BIOSEB’s Postural Module for Dynamic Weight Bearing 2.0 (DWB2) is an optional software add-on that extends DWB2 weight-bearing analysis with quantitative postural metrics. Developed in collaboration with Dr. Tighilet’s laboratory (Aix Marseille Université-CNRS) for anti-vertigo and vestibular studies, the module computes posture support asymmetries, non-limb compensatory load, global activity metrics and rotational/circling behaviors. The module is software-only and compatible with existing DWB2 systems; it can be installed by download and used to re-analyze prior acquisitions with the new parameters.

Key features / Results

• Posture support asymmetries: polygon area of four-limb support (cm²) / max area — calculated from lines joining paw centers; increases indicate imbalance.
• Base of support (forelimbs / hindlimbs, cm) — inter-paw distances; reflects stance changes with imbalance.
• Gravity center vs geometric center distance (cm) — mean offset between barycenter and quadrilateral center.
• Confidence ellipse surface, width and height (cm²) — area containing 90% of barycenter positions; sensitive to postural instability.
• Torsion (cm) — distance between front and rear paw on the same side; quantifies body torsion.

Non-Limb Compensatory Load

• Rearing on tail: count and duration (s) — episodes where tail provides support.
• Wall-supported rearing: count — rearing using cage wall (with/without tail support).
• Abdominal support: weight (g) and duration (s) — weight borne on abdomen and time spent, increasing with imbalance.

Global Activity

• Global distance (cm) — total distance traveled.
• Average speed (cm/s) — mean speed while moving.

Rotations / Circling

• Number of right/left rotations (a.u.) — counts of rotations; direction may indicate lateralization.
• Number of right/left circling (a.u.) — rapid in-place rotations (<500 ms) often associated with unilateral lesions.
• Circling vs rotation — circling defined as fast rotation around center of gravity.

Domains of application

• Vestibular disorders and inner ear dysfunction
• Stroke and unilateral lesion models
• Parkinson’s disease and dopaminergic models
• Neuropathic and chronic pain models
• Developmental gait and balance studies
• Psychiatric research (schizophrenia, Tourette syndrome, ADHD)

Software
The Postural Module is distributed as an optional software upgrade for all DWB2 systems. Installation is performed via software download; no hardware changes are required. Existing datasets can be reprocessed to generate the new postural parameters.

Validation
Validation reported (PubMed ID: 32547480).

Technical specifications

• Reference: BIO-DWB2-POSTUR
• Commercial name: Dynamic Weight Bearing 2.0 – Postural Module
• Compatibility: fully compatible with all DWB2 systems; software-only add-on
• Main measured endpoints: posture support asymmetries, non-limb weight bearing (abdomen & tail), global activity (distance, average speed), rotations & circling
• Installation: software download; re-analysis of existing datasets possible
• Intended subjects: rats and mice
• Product type: software add-on / optional module
• Product ID: 1877
• Product reference/code: BIO-DWB2-POSTUR
• Weight (metadata): 0.000000 kg
• Price (excl. tax): 0.00 (EUR) — displayed as €0.00 on site