Coronary stent SYNERGY™

platinium-chromiumpolymerdrug eluting

Product overview
The SYNERGY™ Everolimus‑Eluting Platinum Chromium Coronary Stent System (SYNERGY BP Stent) is a platinum‑chromium drug‑eluting stent with an abluminal bioabsorbable polymer designed to provide controlled everolimus release and to minimize long‑term polymer exposure following drug elution (~3 months). The system is available with Monorail™ and Over‑The‑Wire delivery options across a broad range of diameters and lengths.

Key clinical and design points

• Everolimus‑eluting stent built on a platinum‑chromium platform for radial strength and conformability.
• Abluminal bioabsorbable polymer coating absorbed shortly after drug elution (approximately 3 months).
• Design intent to promote early endothelial healing and support potential shortened dual antiplatelet therapy (DAPT) in appropriate patients, including those at high bleeding risk.
• First FDA‑approved DES with an abluminal bioabsorbable polymer available in the U.S. (SYNERGY BP Stent).
• Clinical evidence from multiple studies and registries: data from over 18,000 patients across 9 studies demonstrating consistently low stent thrombosis rates.

Intended/highlighted uses and evidence

• Indicated and highlighted for use in patients at high bleeding risk in applicable jurisdictions; clinical design supports early healing and potential for short DAPT where clinically appropriate.
• Consistent safety and performance outcomes reported across randomized trials and real‑world registries, including low rates of stent thrombosis.

Documentation available

• Directions for Use
• Indications, Safety and Warnings
• Product ordering information

Ordering information (summary of available configurations)

Monorail™ delivery system (Ø (mm) | Overexpansion Capabilities)

• 2.25 | 3.50
  Length (mm) | Item number
  8 mm | H7493926008220
  12 mm | H7493926012220
  16 mm | H7493926016220
  20 mm | H7493926020220
  24 mm | H7493926024220
  28 mm | H7493926028220
  32 mm | H7493926032220
  38 mm | H7493926038220
• 2.50 | 3.50
  Length (mm) | Item number
  8 mm | H7493926008250
  12 mm | H7493926012250
  16 mm | H7493926016250
  20 mm | H7493926020250
  24 mm | H7493926024250
  28 mm | H7493926028250
  32 mm | H7493926032250
  38 mm | H7493926038250
• 2.75 | 3.50
  Length (mm) | Item number
  8 mm | H7493926008270
  12 mm | H7493926012270
  16 mm | H7493926016270
  20 mm | H7493926020270
  24 mm | H7493926024270
  28 mm | H7493926028270
  32 mm | H7493926032270
  38 mm | H7493926038270
• 3.00 | 4.25
  Length (mm) | Item number
  8 mm | H7493926008300
  12 mm | H7493926012300
  16 mm | H7493926016300
  20 mm | H7493926020300
  24 mm | H7493926024300
  28 mm | H7493926028300
  32 mm | H7493926032300
  38 mm | H7493926038300
• 3.50 | 4.25
  Length (mm) | Item number
  8 mm | H7493926008350
  12 mm | H7493926012350
  16 mm | H7493926016350
  20 mm | H7493926020350
  24 mm | H7493926024350
  28 mm | H7493926028350
  32 mm | H7493926032350
  38 mm | H7493926038350
• 4.00 | 5.75
  Length (mm) | Item number
  8 mm | H7493926008400
  12 mm | H7493926012400
  16 mm | H7493926016400
  20 mm | H7493926020400
  24 mm | H7493926024400
  28 mm | H7493926028400
  32 mm | H7493926032400
  38 mm | H7493926038400
• 4.50 | 5.75
  Length (mm) | Item number
  12 mm | H7493926012450
  16 mm | H7493926016450
  20 mm | H7493926020450
  24 mm | H7493926024450
  28 mm | H7493926028450
  32 mm | H7493926032450
• 5.00 | 5.75
  Length (mm) | Item number
  12 mm | H7493926012500
  16 mm | H7493926016500
  20 mm | H7493926020500
  24 mm | H7493926024500
  28 mm | H7493926028500
  32 mm | H7493926032500

Over‑The‑Wire delivery system (Ø (mm) | Overexpansion Capabilities)

• 2.25 | 3.50
  Length (mm) | Item number
  8 mm | H7493926108220
  12 mm | H7493926112220
  16 mm | H7493926116220
  20 mm | H7493926120220
  24 mm | H7493926124220
  28 mm | H7493926128220
  32 mm | H7493926132220
  38 mm | H7493926138220
• 2.50 | 3.50
  Length (mm) | Item number
  8 mm | H7493926108250
  12 mm | H7493926112250
  16 mm | H7493926116250
  20 mm | H7493926120250
  24 mm | H7493926124250
  28 mm | H7493926128250
  32 mm | H7493926132250
  38 mm | H7493926138250
• 2.75 | 3.50
  Length (mm) | Item number
  8 mm | H7493926108270
  12 mm | H7493926112270
  16 mm | H7493926116270
  20 mm | H7493926120270
  24 mm | H7493926124270
  28 mm | H7493926128270
  32 mm | H7493926132270
  38 mm | H7493926138270
• 3.00 | 4.25
  Length (mm) | Item number
  8 mm | H7493926108300
  12 mm | H7493926112300
  16 mm | H7493926116300
  20 mm | H7493926120300
  24 mm | H7493926124300
  28 mm | H7493926128300
  32 mm | H7493926132300
  38 mm | H7493926138300
• 3.50 | 4.25
  Length (mm) | Item number
  8 mm | H7493926108350
  12 mm | H7493926112350
  16 mm | H7493926116350
  20 mm | H7493926120350
  24 mm | H7493926124350
  28 mm | H7493926128350
  32 mm | H7493926132350
  38 mm | H7493926138350
• 4.00 | 5.75
  Length (mm) | Item number
  8 mm | H7493926108400
  12 mm | H7493926112400
  16 mm | H7493926116400
  20 mm | H7493926120400
  24 mm | H7493926124400
  28 mm | H7493926128400
  32 mm | H7493926132400
  38 mm | H7493926138400

Multimedia

• Multiple product and educational videos and animations available for clinicians, including product animation, clinical overviews and physician perspectives.

Characteristics / technical specifications

• Drug: Everolimus (drug‑eluting)
• Platform: Platinum‑chromium stent platform
• Polymer: Abluminal bioabsorbable polymer; absorption shortly after drug elution (~3 months)
• Design intent: Promote early healing; reduce long‑term polymer exposure; enable shortened DAPT where clinically appropriate
• Indication highlight: First DES with abluminal bioabsorbable polymer available in the U.S.; indicated/highlighted for patients at high bleeding risk where applicable
• Available diameters: 2.25 mm to 5.00 mm (multiple overexpansion capability up to 5.75 mm depending on nominal size)
• Available lengths: 8 mm, 12 mm, 16 mm, 20 mm, 24 mm, 28 mm, 32 mm, 38 mm (availability varies by diameter and delivery system)
• Delivery systems: Monorail™ and Over‑The‑Wire (OTW)
• Ordering identifiers: Item/UPN numbers provided per diameter/length/delivery system (examples: Monorail 3.00×16 mm = H7493926016300; OTW 3.00×16 mm = H7493926116300)