Thalassemia rapid diagnostic test GTHapScreen® HBB
for medical researchfor genesfor DNA

thalassemia rapid diagnostic test
thalassemia rapid diagnostic test
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Characteristics

Applications
thalassemia, for medical research
Tested parameter
for genes
Sample type
for DNA
Analysis mode
QF-PCR

Description

The unique kit can be used to detect carrier and/or affected sample as well as screen the autosomal markers in a single reaction! The GTHapScreen HBB kit is developed to detect carrier and/or affected sample for Beta Thalassemia. The kit functions on the principle based on STR markers and QF PCR technique to detect carrier or to be patient by linkage analysis. Use of STR markers makes prenatal diagnosis more accurate and reliable. Kit components include multiplex PCR primers which are designed from a HBB gene. This gene is used commonly in carrier detection and prenatal diagnosis of Beta-Thalassemia Disease. STR markers designed from 5 regions that covers the upstream and downstream of the HBB gene. This kit is optimised to use DNA samples purified from blood, amniotic fluid, and chorionic villus (CVS). Along with Beta Thalassemia detection the GTHapScreen HBB kit includes autosomal STR markers for Chromosome 21, 18, 13, X and Y. These markers provide extra advantages along with detection of this disorder. Features Aids carrier detection and prenatal diagnosis Rules out/in sample authenticity, maternal cell contamination It detects uniparental disomy Chromosomal aneuploidy detection Determination of fetus’ sex

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