Microscope slide scanner Aperio GT 450 DX

with barcode readerhigh-speedhigh-resolution

Overview
The Aperio GT 450 DX is an automated, high-capacity digital pathology slide scanner engineered for high-volume clinical and research laboratories. It delivers consistently calibrated diagnostic images using Leica optics and color calibration technology, while enabling streamlined, no-touch workflows and centralized scanner management.

Key Benefits

• Increase throughput with continuous no-touch loading from compatible workstations (e.g., HistoCore SPECTRA) and automatic rack handling.
• Centralize IT control via Scanner Administrator Manager (SAM) server to configure and monitor multiple scanners securely.
• Reduce rescans with automated image quality checks and Leica custom optics for diagnostic-grade images.

Designed for Histotechnicians, IT Professionals and Pathologists
The Aperio GT 450 DX is bench-friendly and optimized for high throughput: prioritise time-critical cases, manage racks during scanning, and integrate into lab workflows while providing IT teams with secure remote monitoring and user management.

Operational Highlights

• 450-slide capacity (15 racks × 30 slides) in a compact footprint.
• No-touch continuous loading during scanning for uninterrupted operation.
• Automated IQ assessments on each slide; every slide calibrated during capture.
• Assign and manage priority cases and racks while scans are in progress.
• 99.5% tissue finder accuracy and 100% first-time barcode scan success in validation tests.

Image Quality
Custom Leica objective with extra-wide flat-field correction maximizes usable field of view (1 mm FOV) and supports high-speed acquisition. Automated image-quality assessment reduces rework and ensures images meet diagnostic requirements.

Real-Time Focusing (RTF)
Real-Time Focusing captures focus data during scanning using a focusing line sensor; proprietary algorithms compute and apply continuous objective adjustments to maintain optimal focus in real time (see product resources for patent references).

Product Specifications (selected)
Magnification: 40x
Scan Speed: 32 sec/slide (@40x for 15 mm × 15 mm area)
Scan Throughput: 81 slides/hr (@40x for 15 mm × 15 mm area)*
Scan Resolution: 0.26 µm/pixel at 40x
Scan Output: SVS (TIFF supported)
Scanning Region: ≤ 23.6 mm × 58 mm
Field of View (FOV): 1 mm
Objective Lens: Custom Leica objective with extra-wide flat-field correction
Slide Capacity: 450 slides (15 racks of 30)
Slide Loading: Automated continuous load for 1" × 3" slides
Racks Accepted: Leica Universal Rack (30-slide), Sakura Prisma racks (20-slide)
Dimensions (W × D × H): 52.83 cm × 71.12 cm × 49.53 cm
Weight: 63.5 kg
Network: 1 Gbps (scanner → SAM); 10 Gbps (SAM → image repository)
Image File Formats: SVS, TIFF
Security: SSL for SAM UI, user-specific PINs per scanner, secure sign-on, logging and remote status access

Slides, Coverslips & Labels
Standard slide size: 2.54 cm × 7.62 cm (1" × 3") ISO 8037/1 compliant
Minimum/Maximum slide size: 25 mm × 75 mm / 26 mm × 76 mm
Optimized tissue thickness: 3–5 µm (including mounting medium)
Coverslips: optimized ~0.17 mm thickness (glass or CTA film)
Label area: 25 mm × 25 mm; labels must be matte, not protruding or attached to slide underside
Supported barcodes: 1D & 2D (NW7, QR, Data Matrix, Interleaved 2 of 5, Code 39, Code 128, PDF417, MicroPDF417)

Notes
For diagnostic review use Aperio DX Viewer on a calibrated Aperio DX Viewing Station; validation results and whitepapers are referenced in product resources.

Characteristics / Technical specifications

• Model: Aperio GT 450 DX
• Magnification: 40x
• Scan resolution: 0.26 µm/pixel (40x)
• Scan speed: ~32 sec/slide (15 mm × 15 mm at 40x)
• Throughput: up to 81 slides/hr (15 mm × 15 mm at 40x)
• Capacity: 450 slides (15 racks × 30)
• Scanning region: ≤ 23.6 mm × 58 mm
• Field of view: 1 mm
• Output formats: SVS, TIFF
• Dimensions (W × D × H): 52.83 cm × 71.12 cm × 49.53 cm
• Weight: 63.5 kg
• Network: 1 Gbps (Scanner→SAM), 10 Gbps (SAM→repository)
• Barcode support: NW7, QR, Data Matrix, Interleaved 2 of 5, Code 39, Code 128, PDF417, MicroPDF417
• Special imaging tech: Real-Time Focusing (RTF)