Microscope slide scanner Aperio GT 450

with barcode readerAI-assistedhigh-speed

Overview
The Aperio GT 450 is a high‑throughput digital pathology scanner designed for research and clinical workflows, combining automated loading, DICOM compatibility and advanced imaging modes for consistent slide digitization.

Key Features and Benefits

• 40+ patents supporting automated workflows and flexible scanning options.
• 32‑second scan time (15 mm x 15 mm at 40x); sustained throughput up to 81 slides/hr at 40x.
• Manual Scan mode for on‑demand re‑scans and parameter adjustment.
• Extended Focus creates a single in‑focus image from multiple layers, reducing storage relative to Z‑Stacks.
• Default Calibration Point and Automated Narrow Stripe to minimize image artifacts.
• DICOM support (20x, 40x and Z‑Stack) for interoperability with clinical systems.
• Aperio iQC (optional): AI‑driven quality checks and dashboard notifications.

Manual Scan — Benefits
Manual Scan addresses variability in slide preparation and enables rapid remediation of image issues, improving usable image yield and workflow continuity.

• Immediate re‑scanning from the same location to accelerate slide delivery.
• Resolves issues such as faint IHC staining, small tissue fragments or low‑density samples.
• Improves results for challenging specimens while reducing manual review time.

Extended Focus — Features
Extended Focus provides an all‑in‑focus single image with lower storage needs than multi‑layer Z‑Stacks, improving usability for thick specimens.

• All cells appear in focus on one image, avoiding layer navigation.
• Smaller file sizes than Z‑Stacks, enabling faster transfer and collaboration.
• Recommended for thick or uneven samples requiring increased depth of field.

DICOM, Magnification & Z-Stacking
Supports common file formats and magnifications to integrate with LIS/PACS environments and to enable multi‑plane review.

• Outputs in .svs and DICOM formats.
• 20x and 40x magnification options for different use cases.
• Z‑Stacking available for multi‑height sample review.

Aperio iQC Software (Optional)
Aperio iQC uses AI to identify WSI artifacts and prioritize slides for review via a QC dashboard.

• AI detection of whole slide image artifacts with notification workflows.
• Automated algorithms to flag substandard slides and focus manual review.

For Lab Managers
Designed for high throughput and continuous operation with easy rack handling and capacity options to match lab demand.

• Maximum capacity: 15 racks of 30 slides (450 slides) or 15 racks of 20 slides.
• Supports direct rack loading (compatible with Leica HistoCore SPECTRA Workstation) and continuous rack loading during scanning.
• Sustained throughput example: 81 slides/hr at 40x (15 mm x 15 mm).

For IT Professionals
Scalable, secure architecture for centralized management and integration with laboratory systems.

• Centralized Scanner Admin Manager (SAM) server for remote setup and monitoring of multiple units.
• Encryption, login controls and comprehensive cybersecurity features.
• Two 10 Gb network links on the SAM server; scalable hub‑and‑spoke deployment.
• HL7 compatibility for integration with LIS/LIMS/PACS and dedicated scanner logins.

Image Quality & Optics
Proprietary focusing and a custom Leica objective deliver consistent focus and a wide usable field of view for high‑resolution capture.

• Real‑Time Focusing (RTF): line sensor provides live focus data and continuous objective adjustment during scanning.
• Custom Leica objective with extra‑wide flat field correction, 1 mm usable FOV and 0.26 μm/pixel resolution at 40x.

Notes
For research use only. Optional features and availability may vary by region.

Technical specifications

• Maximum Slide Capacity: 450
• Rack capacity: 15 racks of 30 slides, 15 racks of 20 slides
• Racks compatible with Leica HistoCore SPECTRA Workstation: Yes
• Continuous rack loading while scanning: Yes
• Priority rack scanning: Yes
• Manual Scan: Yes
• DICOM compatible with 20x, 40x and Z‑Stack: Yes
• Extended Focus: Yes
• Aperio iQC software: Yes (optional)
• Default Calibration Point: Yes
• Automated Narrow Stripe: Yes
• Z‑Stacking: Yes
• Magnification: 20x and 40x
• Resolution: 0.26 μm/pixel at 40x
• Scan speed (15 mm x 15 mm at 40x): 32 sec
• Sustained throughput (15 mm x 15 mm at 40x): 81 slides/hr
• Automated Image Quality Check: Yes
• Slide sizes accepted: 1x3
• Field of View (FOV): 1 mm
• Barcode engines: 1D and 2D symbology
• Dimensions: 20.8” (52.83 cm) W x 28” (71.12 cm) L x 19.5” (49.53 cm) H
• Weight: 140 lbs (63.5 kg)