Research test kit 3850-1AD-6

immunoglobulinimmunoglobulin GIgG

An ELISA designed to detect the native protein – in our most adaptable kit format to match your unique setup. Combine it with your preferred substrate and buffer. Intended use This ELISA Flex kit is intended for the quantification of human IgG in solution. For research use only. Not for use in diagnostic procedures. Reactivity - Human, Non-human primates Specificity - This kit is based on a matched pair of mAbs specific for the Fc part of human IgG. Cross-reactivity - The mAbs react with human IgG and cross-react with IgG from non-human primates (NHP). For more information please check the Cross-reactivity guide section below. The systems reactive with NHPs are either based on cross-reactive human kits or specifically developed monkey kits (NHP). Cross-reactivity verification tests have been performed in ELISpot and/or ELISA by Mabtech and/or by others. Evaluations of assays with less solid evidence of cross-reactivity are shown as symbols within parentheses. Analyte description - Immunoglobulin G (IgG) is the most abundant Ig isotype in serum, making up approximately 80% of all serum immunoglobulins. In humans, there are four subclasses of immunoglobulin G, with the highest serum concentrations of IgG1 followed by IgG2, IgG3, and IgG4. In mice, the IgG subclasses are defined as IgG1, IgG2a/c, IgG2b, and IgG3. The IgG molecule consists of two heavy and two light chains (κ or λ), resulting in a molecule with two arms for antigen binding. High levels of IgG antibodies are induced following the initial IgM response in a typical immune response to antigens.