Research test kit 3020-1A-6

for animalsbacteriafungi

An ELISA designed to detect the native protein – in our most adaptable kit format to match your unique setup. Combine it with your preferred substrate and buffer. Components Capture mAb - MT49A7 Detection mAb - MTP853, biotin Enzyme conjugate - Streptavidin-ALP Standard - Recombinant bovine IL-17A ELISA standard Buffer/Solution - Standard reconstitution buffer Intended use This ELISA Flex kit is intended for the quantification of porcine IL-17A in solution. For research use only. Not for use in diagnostic procedures. Specificity This kit is based on a matched pair of mAbs enabling specific detction of porcine (pig) IL-17A. Shipping and Storage Shipping Shipped at ambient temperature. Storage Store antibodies and enzyme conjugate at 4-8 °C upon receipt. The ELISA standard should be stored at -20 °C. Shelf life At least 18 months from date of receipt. Analyte description - Interleukin 17A (IL-17A) is a potent proinflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8 T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce the expression of cytokines, chemokines, and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells.