Nitric oxide monitoring device NOXtec 1000

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Overview
NOXtec 1000 is a medical device for controlled delivery and continuous monitoring of inhaled nitric oxide (NO). It provides a stable NO dose throughout therapy, supports automatic cylinder exchange and is designed for administration of NO in a mixture with medical oxygen to treat conditions such as pulmonary arterial hypertension.

Operation
NOXtec 1000 automatically calculates the dosing flow required to reach the target PPM using a disposable respiratory flow sensor placed in the patient breathing circuit. The dose rate can also be set manually. By continuously sampling the delivered NO–O2 mixture, the device monitors the nitric oxide concentration received by the patient and verifies compliance with preset thresholds.

Monitoring and Safety
NOXtec 1000 continuously monitors NO, NO2 and O2 concentrations and detects trace amounts of nitrogen dioxide (NO2) to prevent exceeding safety limits. The system performs automatic calibration of NO, NO2 and O2 sensors, including during dosing, reducing the need for manual calibration. It features automatic venting at treatment start and during cylinder exchange, a purge outlet to collect residual gas, room gas measurement capability and an emergency manual dosing function usable when the device is switched off.

Accessories

• Cart: carries up to 2 NO–N2 cylinders (10 L or 20 L).
• Automatic cylinder exchange to extend treatment autonomy and optimize gas use.
• Consumable patient kits to connect the device to a wide range of ventilators.
• Swivel wheels for easy movement.

Dose / Monitor system - summary table
DOSE SYSTEM / MONITOR SYSTEM
Real time mode | Automatic mode | Semiautomatic mode | Manual mode | Cylinder exchange | Automatic venting | Automatic calibration | Room measurement

Key points
Ready to use: no calibration test required before starting therapy. Automatic cylinder exchange and automatic calibration reduce operational workload and accelerate therapy start-up. Continuous sampling ensures real-time concentration monitoring and alarm management to support patient safety.

Characteristics / technical specifications

• Dosing modes: real-time automatic calculation, automatic, semiautomatic and manual.
• Dose calculation based on a disposable respiratory flow sensor installed in the patient circuit.
• Continuous sampling and monitoring of delivered NO concentration to maintain stable PPM throughout therapy.
• Monitoring of NO, NO2 (trace detection) and O2; room measurement possible.
• Automatic calibration of NO, NO2 and O2 sensors; can calibrate while dosing.
• Automatic cylinder exchange system to increase autonomy and optimize gas consumption.
• Automatic venting at treatment start and during cylinder exchange to minimize NO2 exposure to the patient.
• Purge outlet to collect and channel residual gas.
• Emergency manual dosing available even when the device is switched off.
• Cart accessory: supports up to two NO–N2 cylinders (10 L or 20 L); swivel wheels for mobility.
• Consumable kits available for connection to a wide range of ventilators.
• Ready-to-use design: no calibration required before power-up, enabling rapid initiation.